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Multiple Sclerosis
breakthrough procedure, which
involves widening the veins.

Chronic Cerebrospinal Venous Insufficiency CCSVI - Multiple Sclerosis MS Sufferers Have Abnormal Blood Flow In Necks

#ms cure, #multiple sclerosis, #Zamboni, #Interventional Radiologist, 3Chronic Cerebrospinal Venous Insufficiency #CCSVI

Find a controversial new (cure) for multiple sclerosis. Hundreds hear about MS (cure) . Have doctors found a (cure) for ms?

IT MAY NOT CURE YOU - BUT this HAS
CURED some PEOPLE.

 

CLASSIFIED as an autoimmune disease which should now be reclassifed to a Vascular venus disease of the brain.

The information within is provided as is and should not be considered medical advise. Medical treatments are serious decisions and should be done only with the full consent of your physician. “It's eye-opening the way this group of patients has grabbed hold of the social-networking technology,” said Dr. Simon, an interventional radiologist at JFK Medical Center in Edison, N.J. “They've taken this to a level I've not seen in other patients. Patients used to read an article or two. Now, they're actually seeing procedures on YouTube. Is this the future of medicine?”


Dr. Paolo Zamboni Father of CCSVI

 

 

Why don't you know about an interventional radiologist and the "Liberation treatment" from your doctor, or the Multiple Sclerosis Society?

A vascular surgeon by training, Zamboni believes MS is not an autoimmune condition, as widely believed, but rather a vascular disease that can be cured with surgery.

"Liberation treatment" developed by Italian researcher Dr. Paolo Zamboni to combat the disease of the central nervous system. Zamboni postulates that a disorder called CCSVI relates to MS, in that it blocks large veins that drain from the brain and spinal cord, and can be effectively treated by putting special wires in through the groin and passing them up to the blocked areas, opening up the veins. The result, he claims, is a decrease in relapse rate and severity of symptoms.

2006 Zamboni outlines of his theory on how he believed that this is a venous insufficiency problem.

Paolo Zamboni Director of the Centre for Vascular Diseases, University of Ferrara, Ferrara (ITA) He discovered and described CCSVI in MS patientst

2009 article - History of the Big Idea
 Watching his wife Elena struggle with the fatigue, muscle weakness and visual problems of MS led Zamboni to begin an intense personal search for the cause of her disease. He found that scientists who had studied the brains of MS patients had noticed higher levels of iron in their brain, not accounted for by age. The iron deposits had a unique pattern, often forming in the core of the brain, clustered around the veins that normally drain blood from the head. No one had ever fully explained this phenomenon, considering the excess iron a toxic byproduct of the MS itself.
Dr. Zamboni wondered if the iron came from blood improperly collecting in the brain. Using Doppler ultrasound, he began examining the necks of MS patients and made an extraordinary finding.

Almost 100% of the patients had a narrowing, twisting or outright blockage of the veins that are supposed to flush blood from the brain. He then checked these veins in healthy people, and found none of these malformations. Nor did he find these blockages in those with other neurological conditions.

Zamboni emphasizes that the Liberation Treatment does not make people in wheelchairs walk again. Rather, it seems to stop the development of further MS attacks, and in some cases, improves movement and decreases the debilitating fatigue that are the hallmarks of MS. The foundation that has sponsored Zamboni's research, the Hilarescere Foundation, also urges cautious restraint.

HOW IS IT TREATED?
CCSVI first identifies the veins that are blocked using a procedure such as the ECD-TCCS.
After this an appropriately qualified surgeon would be required to operate on the affected veins. The technique employed by Dr Zamboni's team was to insert what he called a balloon into the vein and expand it effectively stretching the vein. For most of his patients the expansion was permanent and once the blockage/restriction was removed their MS symptoms began to dissipate.

Paulo Zamboni, whose solution is to widen the veins using a balloon or thin metal tubes.

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Many experts believe MS is caused by a faulty immune system, but a number of doctors now believe damage caused to the nervous system in MS is actually from poor blood flow in the chest, neck blood flow in the chest, neck and head.

What is CCSVI?
Chronic cerebrospinal venous insufficiency... it's a chronic (ongoing) problem where blood from the brain and spine has trouble getting back to the heart. It's caused by stenosis (a narrowing) in the veins that drain the spine and brain. Blood takes longer to get back to the heart, and it can reflux back into the brain and spine or cause edema and leakage of red blood cells and fluids into the delicate tissue of the brain and spine. Blood that stays in the brain too long creates “slowed perfusion”...a delay in deoxyginated blood leaving the head. This can cause a lack of oxygen (hypoxia) in the brain. Plasma and iron from blood deposited in the brain tissue are also very damaging.

Dr. Zamboni et al' s study: "A Prospective open-label study of endovascular treatment of chronic cerebrospinal venous insufficiency," Journal of Vascular Surgery, December 2009, vol.50 (6), 1345-1358.


How is it diagnosed?

 

Doppler Ultrasound -
Bilateral interior jugular vein blockage

There are a few different protocols, depending on where you live and what is available.
Although perhaps not the only possible method for detecting the condition Dr Zamboni and his team used combined technique of high resolution echo-colour-Doppler (ECD) and transcranial colour coded Doppler sonography (TCCS). Combined they are referred to as an ECD-TCCS which according to his paper this test is non-invasive, repeatable and cost effective. Most importantly it is effective for investigating the outflow of blood from the brain. This test is non-invasive, repeatable and cost effective. Most importantly it is effective for investigating the outflow of blood from the brain.
In Italy, Dr. Zamboni begins with a doppler ultrasound of the neck and brain, to see if the blood is refluxing [ see demo ] then he performs a venography. This is where dye is injected into your veins to see the blood flow and possible stenosis. Jacobs Neurological Institute is following this protocol and also using MRV (magnetic resonance venography) An outline of what Dr Zamboni and his team performed is available in his research paper: Doppler haemodynamics of cerebral venous return.

WHERE CAN
I GET TREATED?

 

WHERE CAN I GET TREATED CLINICAL TRIALS:
Look for an Interventional Radiologist, Chronic Cerebrospinal Venous Insufficiency (CCSVI)

Tags: CCSVI, Interventional Radiology, MS, Multiple, Doppler Ultrasound, Chronic Cerebrospinal Venous Insufficiency (CCSVI)

A large-scale treatment trial of the Liberation Procedure has been approved here in the US. Dr. Manish Mehta, working out of Albany, New York, has been given approval to begin a 600 patient trial, scheduled to start in August 2010 and finish in September 2011

Georgetown University Hospital a neurologist & an interventional radiologist are working together.

NY The University of Buffalo's Neuroimaging Analysis Center (BNAC) has found that 55% of those suffering from Multiple Sclerosis have reduced flow in the veins leading from the brain.
This was the first blinded clinical study to examine connections between Chronic Cerebrospinal Venous Insufficiency and MS which were suggested by Zamboni. The University of Buffalo examined 500 adults and children (280 with MS) and found that while 55% of those with MS had signs of CCVI, just 22.4% of those without MS showed similar signs. This suggests that CCVI might indeed have some link to MS.

According to the NMSS Zamboni's own wife who was one of the first patients who underwent an angioplasty style treatment for her MS and who has not had MS symptoms for years, remains on her standard immunomodulatory medications.

BNAC says that its clinical studies are not treatments for MS and that the CTEVD study does not provide subjects with any medical benefits.

However, people with M.S. want to try this procedure now and do not want to wait! Think, a Cardiovascular specialist might be the one to have found one of the causes of MS.

The loss of integrity of the blood-brain barrier, which is primarily built by tight-junction complexes between adjacent endothelial cells of the cerebrovascular endothelium, is a hallmark of multiple sclerosis. The integrity of the blood-brain barrier is primarily executed by tight junctions between cerebrovascular endothelial cells. Thus, the disassembling of tight junctions is a critical point in the development of multiple sclerosis.
In case of a cholesterol problem the blockage will reoccur because of a new cholesterol build up around the vein. therefore the stent will be placed in this case. In the case of MS, once the vein has been 'liberated' it will remain open.

Places where CCSVI is being studied

 

 

SUPPORT GROUP

Buffalo:
CCSVI: Dr. Levy and Dr. Siddiqui's segment Part 1
CCSVI: Dr. Levy and Dr. Siddiqui's segment Part 2

The funded investigators, which include an integration of both MS and vascular experts, report progress in establishing their teams, putting their protocols in place, recruiting participants and beginning their studies, as summarized below.

• Dr. Brenda Banwell, The Hospital for Sick Children, Toronto, Ontario: Her team received Research Ethics Board approval in the fall and has begun enrolling participants and studying vein abnormalities in children and teenagers who have MS, and healthy controls of the same age, using non-invasive MRI measures of vein anatomy and novel measures of venous flow, as well as ultrasound. The team's ultrasound experts have received training in Dr. Zamboni's original techniques.
Read details of Dr. Banwell's plans.

• Dr. Fiona Costello, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta: Her team received Research Ethics Board approval in the fall to begin recruiting a cross-section of people with MS compared to other neurological diseases and healthy volunteers. They also recruited two ultrasonography experts who have begun ultrasound scanning as originally used by Dr. Zamboni. Dr. Costello's team slowed recruitment briefly to upgrade to a new 3T MRI machine (twice as strong as standard clinical MRI) that will be used to perform MR venography scans to compare against the ultrasound tests.
Read details of this team's plans.

• Dr. Aaron Field, University of Wisconsin School of Medicine and Public Health, Madison: His team will be using MR venography and ultrasound techniques originally used by Dr. Zamboni to investigate CCSVI in people with early and later MS, controls with other conditions and healthy volunteers. A study coordinator is developing a recruitment list and an ultrasound expert has been hired and is slated to receive training in the Zamboni techniques. Dr. Field has been negotiating with the Institutional Review Board on issues related to study details and informed consent, and hopes to have these issues resolved to obtain IRB approval in the coming weeks so that scanning can begin.
Read details of this team's plans.

• Dr. Robert Fox, Cleveland Clinic, Cleveland: His team has received Institutional Review Board approval for using MR venography, ultrasound, MRI and clinical measures in people with MS or who are at risk for MS (CIS) and comparison groups, and recruitment is ongoing. Two ultrasound researchers underwent training in the technique originally used by Dr. Zamboni, and the team has obtained a new ultrasound machine previously used in other CCSVI studies. The ultrasound team found several aspects of the published methodology ambiguous, and they have standardized the protocol and analysis to achieve consistent results. To share ideas and solutions to these methodological challenges, Dr. Fox's team has submitted an abstract for consideration for presentation at the American Academy of Neurology's annual meeting in April.
Read details of this team's plans. 

• Dr. Carlos Torres, The Ottawa Hospital, University of Ottawa, Ontario: His team obtained Research Ethics Board approval in the winter and at once began the first phase of scanning using MR venography in people without MS, which will be used to compare with various scans in people with MS. Dr. Torres's team has overcome several obstacles including negotiating with the Research Ethics Board over elements of the informed consent form used to explain the study's procedures and potential outcomes to participants. Team members are slated to be trained using the ultrasound techniques originally used by Dr. Zamboni, and they are on track recruiting more participants for the study.
Read details of this team's plans.

• Dr. Anthony Traboulsee, UBC Hospital MS Clinic, UBC Faculty of Medicine and Dr. Katherine Knox, Saskatoon MS Clinic, University of Saskatchewan: The teams at both sites have received Research Ethics Board approval and have begun to recruit and scan participants. Their ultrasound technologists were trained by Dr. Zamboni, and they are also using catheter venography and MR venography to investigate the prevalence of CCSVI in people with MS and controls without MS. The radiologists on the teams of Drs. Traboulsee and Knox are meeting in February 2011 to ensure the consistency of their protocols across sites. The teams are on target for accrual of recruits and completion of the study.
Read details of their plans.

• Dr. Jerry Wolinsky, University of Texas Health Science Center at Houston: His team applied in advance and obtained Institutional Review Board approval in the spring, and the team's neurosonographer has received intensive training for intracranial and extracranial ultrasound scanning techniques. The team has already scanned a significant number of participants, which includes people with different types of MS, people with other conditions, and people with no known health problems. One obstacle Dr. Wolinsky's team is addressing is the difficulty of recruiting non-MS control subjects who don't have a personal interest in the purpose of the trial. The team is testing whether other imaging methods can confirm the ultrasound findings, while identifying the most reliable technique to screen for CCSVI.
Read details of this team's plans.


The CCSVI Pioneers

 

 

MEDIA

 

 

 

M$$
6 billion busine$$

 

BOYCOTT THE MS SOCIETY

FIGHT - FOR YOUR CHANCE TO HAVE THE SURGERY.
FIGHT - FOR YOUR RIGHT TO CHOICE THAT OPTION.
FIGHT - FOR A YOUR MONEY
FIGHT - 10'S OF THOUSANDS OF SURGERIES = DATA
FIGHT - FOR MORE DATA = PROVES IT WILL WORK !!
FIGHT - TO PUT THE MS SOCIETY AND EVERYONE WHO MAKES MONEY ON THE DISEASE OUT OF BUSINESS.

There are 2 groups.
Those who live off MS and those who live with it.

The testing for chronic cerebrospinal venous insufficiency (CCSVI) poses no risk to patients and the treatment, balloon angioplasty, is well known and low risk. It is not experimental and has been used around the world since 1973. The only people who are denied testing and treatment for CCSVI venous malformations are those individuals who have been diagnosed with MS.

All these people who work for the MS Society will loose their jobs, immune system doctors loose their income, and Big Pharma will lose the research revenue. There is no reason to stop Radioligists from doing this work. Controvery about procedures happen all the time when new ways of doing things come along. Some doctors choose the old way, some learn how to do the new one.

Making Money since 1946 - this charity only gets a 3 star rating.

Every State has their own Multiple Sclerosis Chapter that files form 990. ONLINE Form 990 from Chapters all over the U.S. Some tax-exempt organizations have their most recent federal annual informational tax return Form 990 available on their web site. Some will send you a copy by email. Charities must make the forms for the previous three years available for public inspection at the charity's main office.

WHAT IS WRONG WITH CANADA - they refuse to do trials and you can contact them and let them know they are wrong.
From the Globe: Yves Savoie, president of the MS Society of Canada, said a true clinical trial must be conducted at more than one institution and in more than one province. Because MS is so variable, “it will require well over 1,000 participants that will be recruited through a number of centres,” he said. “A single province or a single site would simply not be a way to get to the definitive answers that we all want.”
If the MS Society thinks a single, giant experimentum crucis is advisable, it would be fair to ask why it isn't advocating one, instead of funding CCSVI research in dribs and drabs. The fact is that piecemeal accumulation is the usual means of accumulating scientific knowledge. There's no unitary global Science Court where hypotheses can be hauled in for exoneration or hanging. [source]

The MS Society in Canada got a poor rating as they gobble up whopping 48% of their revenue spent on administration and management.

WALL STREET
& K STREET

FUNDING POLITICIANS' CAMPAIGN PROTECTS BUSINESS $UPPLY cHAIN
WASHINGTON IS SUPPOSED TO WORK FOR THE PEOPLE.

NO MONEY - NO VOICE YOU HAVE TO PAY TO PLAY

A LOBBYIST WORKS FOR THE COORPORATION.

Watch Movie: Casino Jack and the United States of Money
Documentarian Alex Gibney (Enron: The Smartest Guys in the Room) turns his acute focus on convicted Washington lobbyist Jack Abramoff, reproaching him and other legislators for their negative impact on U.S. politics. Gibney's film plays less like a dry treatise and more like a high-stakes political thriller, fearlessly examining the ways American policies and political processes are undermined by an endless quest for power.

Example: Google's CEO: 'The Laws Are Written by Lobbyists'
Google 2.4% Rate Shows How $60 Billion Lost to Tax Loopholes
Transfer Pricing - The tactics of Google and Facebook depend on “transfer pricing,” paper transactions among corporate subsidiaries that allow for allocating income to tax havens while attributing expenses to higher-tax countries.

M$$ LOBBY SPENT $94,501.00 FOR THIS REPORTING PERIOD Q2 7/15/2010

WHO GOT THE MONEY:

Whose Campain Fund got rewarded?

Name of each individual who acted as a lobbyist in this issue area:

Laura Weidner, Manager, Federal Relations
(202) 408-1500 laura.weidner@nmss.org
Senate ID# 69674-12
House ID# 357890000
expenses 2009

Shawn O'Neail, who started to use online tool called Capwiz to help lobbyists manipulate washington with email from "supporters".
Capwiz is CQ-Roll Call Group 1255 22nd Street N.W. · Washington, D.C. 20037 · 202-419-8500 Reach nearly 100,000 political insiders every day through the CQ-Roll Call Group network. Track legislation in all 50 states with CQ StateTrack—the comprehensive and customizable state legislative tracking service. This exciting product enables you to pinpoint the bills and amendments in state legislatures that affect your interests.

Lauren Chiarello, Director, Federal Affairs
202-408-1500 or via email at lauren.chiarello@nmss.org

ADDENDUM for General Lobbying Issue Area:
BUD - BUDGET/APPROPRIATIONS well as inclusion of language in the Committee report urging the NIH to further research
biomarkers for multiple sclerosis and primary progressive MS.

Line 16. Specific lobbying issues
-Department of Defense Appropriations Act, 2011,
support funding for multiple sclerosis research in the Congressionally
Directed Medical Research Programs (CDMRP).
-Department of Labor, Health and Human Services, Education Appropriations Act, 2011, support funding for the Lifespan
Respite Care Act, the Cures Acceleration Network, the National Institutes of Health (NIH), the Social Security Administration, as U.S. HOUSE OF REPRESENTATIVES, U.S. SENATE, Administration on Aging, Defense
- Dept of (DOD), Health & Human Services
- Dept of (HHS), Centers For Medicare and Medicaid Services
(CMS), Social Security Administration (SSA)

FYI: The American Autoimmune Related Diseases Association (AARDA) and The National Coalition of Autoimmune Patient Groups (NCAPG) also has a Lobby at work.


Carrie Radant National Director, Donor Development
303.698.6100 x 15165, carrie.radant@nmss.org

"Interventional Radiology" DISRUPTS THE $UPPLY CHAIN
If MS PATIENTS get better using something very simple, EVERYONE ABOVE LOOSES MONEY and JOBS including the MS Society. People who are running out of time need to try something simple.

FINDING A CURE FOR MS MEANS NO MORE MONEY FOR:
- NON PROFIT BIG BUSINESS Multiple Sclerosis Society and all the Chapters Total Income $374,220,024
- Insurance Company - Long Term Care Companies
- The Drug Company
- University Schools of Medcine - Department of Neurology and Neuroscience Institutes, Immune System Docs
- Hospitals who run Multiple Sclerosis Research and Clinical Programs
- Physicians who run Multiple Sclerosis Research and Clinical Programs
- Print Publishers and Authors who sell information on how to get insurance for MS
- Online Publishers and Authors like WEBMD and the Cleveland Clinic who report Doctors still don't understand what causes MS but sell their ignorant information.

Society of Interventiaonal Radiology
Interventional Radiology (abbreviated IR or sometimes VIR for vascular and interventional radiology) is a subspecialty of radiology in which minimally invasive procedures are performed using image guidance. Some of these procedures are done for purely diagnostic purposes (e.g., angiogram), while others are done for treatment purposes (e.g., angioplasty). Images are used to direct these procedures, which are usually done with needles or other tiny instruments like small tubes called catheters. The images provide road maps that allow the Interventional Radiologist to guide these instruments through the body to the areas containing diseases.

Common IR procedures are:
* Angiography: imaging the blood vessels to look for abnormalities with the use of various contrast media, including iodinated contrast, gadolinium based agents, and CO2 gas.
* Balloon angioplasty/stent: opening of narrow or blocked blood vessels using a balloon; may include placement of metallic stents as well (both self-expanding and balloon expandable).

Prof. Dake gives a presentation at the annual meeting of interventional radiologists about stenting jugular veins for MS.

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Part 2 - Part 3

 

THE Turf Wars
CARTELS CONTROL
YOUR CHOICE!

 

IT IS COMMON TO HAVE A DIFFERENCE OF OPINON BETEEN DOCTORS INSIDE THE MEDICAL DISCIPLINE ABOUT THE BEST TREATMENT FOR A PATIENT. THIS IS A LEGITIMATE WAY OF PROVIDING MEDICAL TREATMENT.

It is legitimate when some doctors believe the old way is the best way, AND others believe the NEW WAY is better.

DOCTORS ARE ALLOWED TO PROVIDE TREATMENT / SURGERY WITHOUT LAWYERS SHUTING THEM DOWN.

Regarding CCSVI this isn't a difference of opinion inside the same discipline. This is the TURF WARS between Radiolology vs. Department of Neurology and Neuroscience Institutes, Immune Diseases.

Q: WHY ARE THE LAWYERS INVOLVED IN SHUTING DOWN ?
A: FOLLOW THE MONEY

Complain to
Dr. Mark Freedman, director of the MS research unit
NATIONAL MULTIPLE SCLEROSIS SOCIETY
733  3rd Av  6th Fl
New York  City  10017-3288 
(212) 986-3240
EIN 13-5661935

Demand that Kimberly Calder Director of Insurance Initiatives, National Multiple Sclerosis Society advocate for you!

Kimberly Calder
733 Third Avenue
New York, NY 10017
Office: 212-476-0450
Fax: 212-476-0485
Kim.Calder@nmss.org
Every state has a Department of Insurance. Medicare www.medicare.gov supplemental insurance policy also known as a Medigap policy. Medicaid is health insurance for people with very low incomes and low assets.

Karen Lee, Ph.D.
Assistant Vice-President, Research - Research and Programs Department
Multiple Sclerosis Society of Canada
msgrants@mssociety.ca

You can also get a copy of the federal annual informational tax return Form 990 from the Disclosure Office of any IRS District Office. It is necessary to have the employer identification number of the charity. Look at the Form 990, you will find out how much the charity spent for fundraising fees, salaries and more.
Very few so-called charitable organizations will send you this information. When they do, it is usually incomplete. You can judge an organization's practices, as well as its veracity, by asking them to send you a copy of their federal Form 990. All federally tax-exempt nonprofit organizations that have $25,000.00 or more of gross receipts for the year are required to file this annual informational tax return. Most national charities are divided into chapters.
When a solicitor telephones you regarding a charity, say:

INSURANCE

 

 

The National Association of Insurance Commissioners (NAIC) recently named eighteen funded and ten unfunded consumer liaison representatives for 2010. Seven of the funded consumer representatives participated in the program in 2009, while eleven are new to the NAIC program. Find 2010 NAIC funded consumer liaison representatives.

National Multiple Sclerosis Society Clinical Advisory Board, Executive Committee

2010 NAIC UNFUNDED CONSUMER REPRESENTATIVES PDF
Formed in 1871, the National Association of Insurance Commissioners (NAIC) is a voluntary organization of the chief insurance regulatory officials of the 50 states, the District of Columbia and five U.S. territories. The NAIC has three offices: Executive Office, Washington, D.C.; Central Office, Kansas City, Mo.; and Securities Valuation Office, New York City. The NAIC serves the needs of consumers and the industry, with an overriding objective of supporting state insurance regulators as they protect consumers and maintain the financial stability of the insurance marketplace. For more information, visit www.naic.org.

 

DRUGS

 

THERE IS NO CURE FOR MULTIPLE SCLEROSIS.

Treatment typically focuses on combating the autoimmune response and managing the symptoms. Some people have such mild symptoms that no treatment is necessary.

Copaxone COSTS FIVE THOUSAND DOLLARS A MONTH IN THE US. Glatiramer acetate is currently being sold as Copaxone R, a registered trade mark owned by Teva Pharmaceutical Industries Limited. Teva has reported that worldwide sales of Copaxone-R were more than US $1.7 billion in 2007. With the approval of glatiramer acetate generic injectable, global sales of the drug may reach as much as $3 billion this year, Natco Pharma said in a statement. Teva also received the USFDA approval for its abbreviated new drug application (ANDA) for glatiramer acetate Injection, a generic version of Teva Pharmaceutical Industries Ltd.'s treatment for multiple sclerosis.

Drugs that are commonly used for multiple sclerosis include:

 

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